KaloBios(美國)

KaloBios Pharmaceuticals

美國KaloBiosPharmaceuticalswww.kalobios.comHumaneering（TM）是KaloBios制藥的專利治療方法，用于將非人體抗體轉為應用于治療藥物的工程人體抗體。該系統具有保持抗原決定基特異性和提高親和性的優點。KaloBios正在有限的基礎上提供利用humaneering（TM）功能的機會。KaloBiosPharmaceuticals,Inc.,aU.S. based,privatemonoclonalcompany,usesitsbiologiccapabilitiesanditsproprietaryplatformtechnologytodevelopfirst-in-classhumanantibodytherapeutics.ThecompanyhasmultipleprogramsthatwereinsevenPhase1or2clinicaltrialsin2008/09:KB001isananti-infectiveforPseudomonasaeruginosainfectionsbeingtestedincysticfibrosisandinintensivecarepatientsonaventilator,andKB002andKB003arebeingevaluatedininflammatoryconditions,suchasrheumatoidarthritisandasthma.KB004isinpreclinicaldevelopmentforoncology,andthecompanyplanstofileanINDforitin1H2010.Thecompany抯Humaneering?technologyoffersadvantagesoverothermethodsofhumanantibodycreationintermsofimmunogenicity,potency,andmanufactur